Interactor 1: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Interactor 2: ZDH17 (Q8IUH5)
Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Acyltransferase ZDHHC17) (EC 2.3.1.-) (DHHC domain-containing cysteine-rich protein 17) (DHHC17) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17)
Gene: ZDHHC17

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.740

The method score is based on:

Property Details
Experiments 24705354, 12393793, 9700202, 23275563, 32814053, 15603740
Identification Methods two hybrid, pull down, affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid, two hybrid prey pooling approach, enzymatic study
Interaction Type direct interaction, physical association, palmitoylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005794 - Golgi apparatus
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 3142
Hs

1 632
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024