Interactor 1: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Interactor 2: HEY2 (Q9UBP5)
Hairy/enhancer-of-split related with YRPW motif protein 2 (Cardiovascular helix-loop-helix factor 1) (hCHF1) (Class B basic helix-loop-helix protein 32) (bHLHb32) (HES-related repressor protein 2) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HRT-2) (hHRT2) (Protein gridlock homolog)
Gene: HEY2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.582

The method score is based on:

Property Details
Experiments 23275563
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, luminescence based mammalian interactome mapping
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 3142
Hs

1 337
+ Hs
+ Hs

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Last updated: 15 Jul 2024