HitPredict

Interactor 1: UTP10 (P42945)
U3 small nucleolar RNA-associated protein 10 (U3 snoRNA-associated protein 10) (U three protein 10) (U3 protein 10 required for transcription) (t-UTP10)
Gene: UTP10

Interactor 2: UTP21 (Q06078)
U3 small nucleolar RNA-associated protein 21 (U3 snoRNA-associated protein 21) (U three protein 21)
Gene: UTP21

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.730

Property	Details
Experiments	12150911, 28600509, 16429126, 29263326, 37968396, 38000371
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0030490 - maturation of SSU-rRNA GO:0030686 - 90S preribosome GO:0032040 - small-subunit processome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1769 Sc			1 939
+	Sc
		792630 UTP10_YEAST (1-1769): 0: 1887: 100.00		UTP12_YEAST (11-323): 6.77e-59: 220: 10.06
+	Sc
		630872 UTP10_YEAST (1-1769): 0: 1887: 100.00		NLE1_YEAST (498-782): 6.55e-57: 206: 12.69
+	Sc
		635596 UTP10_YEAST (1-1769): 0: 1887: 100.00		PWP2_YEAST (2-230): 8.49e-13: 74.6: 8.86
+	Hs
		903519 HEAT1_HUMAN (1-435): 2.59e-133: 463: 23.71		WDR5_HUMAN (616-781): 6.74e-26: 111: 14.97
+	Hs
		1331918 HEAT1_HUMAN (1-435): 2.59e-133: 463: 23.71		NLE1_HUMAN (653-785): 5.4e-17: 86.9: 9.70
+	Dm
		1001721 HEAT1_DROME (2-388): 2.48e-107: 383: 24.62		Q0KHS0_DROME (499-657): 5.24e-09: 62.4: 28.40