Interactor 1: EAA1 (P43003)
Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3)
Gene: SLC1A3

Interactor 2: EAA1 (P43003)
Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3)
Gene: SLC1A3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 28424515
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SDF~SDF
Common GO terms GO:0001504 - neurotransmitter uptake
GO:0005313 - L-glutamate transmembrane transporter activity
GO:0005314 - high-affinity L-glutamate transmembrane transporter activity
GO:0005886 - plasma membrane
GO:0006811 - monoatomic ion transport
and 37 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 542
Hs

1 542
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Ph
+ Tk

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024