HitPredict

Interactor 1: GDF5 (P43026)
Growth/differentiation factor 5 (GDF-5) (Bone morphogenetic protein 14) (BMP-14) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Lipopolysaccharide-associated protein 4) (LAP-4) (LPS-associated protein 4) (Radotermin)
Gene: GDF5

Interactor 2: SPB13 (Q9UIV8)
Serpin B13 (HaCaT UV-repressible serpin) (Hurpin) (Headpin) (Peptidase inhibitor 13) (PI-13) (Proteinase inhibitor 13)
Gene: SERPINB13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 501 Hs			1 391
+	Hs
		397015 GDF5_HUMAN (1-501): 0: 605: 100.00		PAI2_HUMAN (1-391): 9.7e-160: 457: 37.26
+	Hs
		271855 GDF5_HUMAN (1-501): 0: 605: 100.00		SPB7_HUMAN (1-391): 5.52e-144: 415: 37.50
+	Hs
		738729 GDF5_HUMAN (1-501): 0: 605: 100.00		SPB5_HUMAN (1-391): 1.32e-135: 394: 32.07
+	Hs
		233928 GDF9_HUMAN (94-501): 5.26e-80: 258: 17.80		SPB9_HUMAN (1-391): 1.91e-165: 469: 41.73