Interactor 1: LIS1 (P43034)
Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
Gene: PAFAH1B1

Interactor 2: LIS1 (P43034)
Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
Gene: PAFAH1B1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.932

The method score is based on:

Property Details
Experiments 11889140, 32341549, 37071682, 12885786, 16258276
Identification Methods affinity chromatography technology, x-ray crystallography, pull down, cross-linking study, two hybrid
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains LisH~LisH, WD40~WD40
Common GO terms GO:0000132 - establishment of mitotic spindle orientation
GO:0000226 - microtubule cytoskeleton organization
GO:0000235 - astral microtubule
GO:0000776 - kinetochore
GO:0001667 - ameboidal-type cell migration
and 78 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 410
Hs

1 410
+ Mm
+ Hs
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024