Interactor 1: LIS1 (P43034)
Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
Gene: PAFAH1B1

Interactor 2: PA1B2 (P68402)
Platelet-activating factor acetylhydrolase IB subunit alpha2 (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH subunit beta) (PAFAH subunit beta)
Gene: PAFAH1B2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.952

The method score is based on:

Property Details
Experiments 10727864, 33961781, 27173435, 37689310, 19622634, 12885786
Identification Methods pull down, affinity chromatography technology, two hybrid, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Lipase_GDSL_2~WD40
Common GO terms GO:0005829 - cytosol
GO:0008247 - 1-alkyl-2-acetylglycerophosphocholine esterase complex
GO:0016042 - lipid catabolic process
GO:0046982 - protein heterodimerization activity
GO:0070062 - extracellular exosome
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 410
Hs

1 229
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024