HitPredict

Interactor 1: LIS1 (P43034)
Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
Gene: PAFAH1B1

Interactor 2: MARE1 (Q15691)
Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1)
Gene: MAPRE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	27173435, 35271311
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000132 - establishment of mitotic spindle orientation GO:0005813 - centrosome GO:0005829 - cytosol GO:0005881 - cytoplasmic microtubule GO:0051010 - microtubule plus-end binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 410 Hs			1 268
+	Hs
		792990 LIS1_HUMAN (1-410): 7.96e-137: 399: 100.00		MARE2_HUMAN (1-267): 3.67e-121: 350: 55.16
+	Hs
		903249 WDR5_HUMAN (4-323): 1.79e-70: 226: 25.38		MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00
+	Hs
		1077066 SNR40_HUMAN (328-408): 1.73e-17: 85.2: 26.83		MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00
+	Hs
		1075058 POC1A_HUMAN (263-407): 1.05e-27: 115: 24.83		MARE2_HUMAN (1-267): 3.67e-121: 350: 55.16