HitPredict

Interactor 1: LIS1 (P43034)
Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
Gene: PAFAH1B1

Interactor 2: NDE1 (Q9NXR1)
Nuclear distribution protein nudE homolog 1 (NudE)
Gene: NDE1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.60 0.718

The method score is based on:

Property Details
Experiments 27173435, 10931877, 34079125, 37689310, 12885786
Identification Methods affinity chromatography technology, two hybrid, proximity labelling technology, pull down, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000132 - establishment of mitotic spindle orientation
GO:0000776 - kinetochore
GO:0001764 - neuron migration
GO:0005813 - centrosome
GO:0005829 - cytosol
and 5 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 410
Hs

1 335
+ Rn
+ Mm
+ Hs
+ Mm
+ Dm
+ Ce
+ An
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024