HitPredict

Interactor 1: LIS1 (P43034)
Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
Gene: PAFAH1B1

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 410 Hs			1 2752
+	Hs
		1346970 NLE1_HUMAN (1-219): 4.29e-44: 161: 22.51		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		1288394 SNR40_HUMAN (328-408): 1.73e-17: 85.2: 26.83		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		903450 WDR5_HUMAN (4-323): 1.79e-70: 226: 25.38		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		929494 RACK1_HUMAN (103-261): 2.66e-16: 80.9: 33.13		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Hs
		903375 WDR5_HUMAN (4-323): 1.79e-70: 226: 25.38		BD1L1_HUMAN (16-2752): 1.77e-19: 99.2: 9.13
+	Hs
		929620 RACK1_HUMAN (103-261): 2.66e-16: 80.9: 33.13		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1302927 NLE1_HUMAN (1-219): 4.29e-44: 161: 22.51		MINT_HUMAN (709-2695): 5.55e-37: 157: 9.30
+	Hs
		820867 WDR5_HUMAN (4-323): 1.79e-70: 226: 25.38		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Mm
		903669 WDR5_MOUSE (4-323): 1.79e-70: 226: 25.38		KMT2C_MOUSE (2097-2749): 1.31e-09: 66.6: 8.68
+	Hs
		903374 WDR5_HUMAN (4-323): 1.79e-70: 226: 25.38		KMT2C_HUMAN (1760-2747): 2.06e-09: 65.9: 9.01
+	Hs
		152622 WDR5_HUMAN (4-323): 1.79e-70: 226: 25.38		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		152663 WDR5B_HUMAN (4-323): 1.45e-69: 224: 25.99		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		1288258 SNR40_HUMAN (328-408): 1.73e-17: 85.2: 26.83		MINT_HUMAN (709-2695): 5.55e-37: 157: 9.30
+	Hs
		1281391 FBXW7_HUMAN (261-409): 5.02e-27: 115: 30.00		PRR36_HUMAN (351-1530): 2.27e-26: 121: 9.95
+	Hs
		1264784 SNR40_HUMAN (328-408): 1.73e-17: 85.2: 26.83		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		1281353 FBXW7_HUMAN (261-409): 5.02e-27: 115: 30.00		DIDO1_HUMAN (13-1216): 9.01e-11: 70.1: 10.22
+	Hs
		152678 FBXW7_HUMAN (261-409): 5.02e-27: 115: 30.00		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		820878 RACK1_HUMAN (103-261): 2.66e-16: 80.9: 33.13		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		929744 RACK1_HUMAN (103-261): 2.66e-16: 80.9: 33.13		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11