HitPredict

Interactor 1: CDK1 (P43063)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 28) (Cell division protein kinase 2)
Gene: CDC28

Interactor 2: HGC1 (Q5ABE2)
Hypha-specific G1 cyclin-related protein 1
Gene: HGC1

Species: Candida albicans SC5314

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	17673907, 20639857, 15071502
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cyclin_N~Pkinase
Common GO terms	GO:0004672 - protein kinase activity GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Ca			1 785
+	Ca
		793055 CDK1_CANAL (1-317): 1.47e-147: 419: 100.00		CG11_CANAL (29-704): 1.99e-120: 379: 18.94
+	Hs
		303829 CDK2_HUMAN (4-298): 5.29e-157: 442: 64.75		CCNB2_HUMAN (2-401): 1.93e-95: 304: 13.18
+	Hs
		538471 CDK2_HUMAN (4-298): 5.29e-157: 442: 64.75		CCNB1_HUMAN (28-389): 1.9e-86: 282: 13.86
+	Hs
		625350 CDK2_HUMAN (4-298): 5.29e-157: 442: 64.75		CCNA1_HUMAN (60-388): 7e-82: 271: 13.64
+	Hs
		303821 CDK1_HUMAN (4-297): 1.68e-142: 405: 63.95		CCNB2_HUMAN (2-401): 1.93e-95: 304: 13.18
+	Hs
		625194 CDK2_HUMAN (4-298): 5.29e-157: 442: 64.75		CCNF_HUMAN (63-576): 2.7e-77: 267: 10.94
+	Hs
		538521 CDK3_HUMAN (4-313): 1.51e-148: 420: 62.90		CCNB1_HUMAN (28-389): 1.9e-86: 282: 13.86
+	Hs
		590125 CDK2_HUMAN (4-298): 5.29e-157: 442: 64.75		CCNA2_HUMAN (2-388): 7.54e-76: 254: 13.20
+	Xl
		526765 CDK1A_XENLA (4-301): 8.08e-143: 406: 62.42		CCNB1_XENLA (6-401): 5.4e-88: 285: 12.12
+	Rn
		70081 Q6P751_RAT (4-298): 1.56e-156: 440: 64.75		B1WC54_RAT (1-421): 6.73e-75: 251: 12.38
+	Mm
		956329 CDK2_MOUSE (4-298): 5.5e-148: 421: 55.69		CCNA1_MOUSE (39-388): 3.27e-82: 270: 13.35
+	Hs
		624539 CDK2_HUMAN (4-298): 5.29e-157: 442: 64.75		CCNE1_HUMAN (1-416): 1.04e-73: 247: 13.48
+	Hs
		414711 CDK1_HUMAN (4-297): 1.68e-142: 405: 63.95		CCNB1_HUMAN (28-389): 1.9e-86: 282: 13.86
+	Mm
		851183 CDK2_MOUSE (4-298): 5.5e-148: 421: 55.69		CCNA2_MOUSE (7-388): 3.14e-77: 257: 13.14
+	Hs
		590162 CDK3_HUMAN (4-313): 1.51e-148: 420: 62.90		CCNA2_HUMAN (2-388): 7.54e-76: 254: 13.20
+	Mm
		956330 CDK2_MOUSE (4-298): 5.5e-148: 421: 55.69		CCNE1_MOUSE (1-421): 2.59e-75: 251: 12.38
+	Hs
		624573 CDK3_HUMAN (4-313): 1.51e-148: 420: 62.90		CCNE1_HUMAN (1-416): 1.04e-73: 247: 13.48
+	Hs
		414732 CDK1_HUMAN (4-297): 1.68e-142: 405: 63.95		CCNA2_HUMAN (2-388): 7.54e-76: 254: 13.20
+	Hs
		414745 CDK1_HUMAN (4-297): 1.68e-142: 405: 63.95		CCNE1_HUMAN (1-416): 1.04e-73: 247: 13.48
+	Ca
		793063 CDK1_CANAL (1-317): 1.47e-147: 419: 100.00		CG21_CANAL (14-362): 6.63e-51: 187: 15.72