HitPredict

Interactor 1: PF2R (P43088)
Prostaglandin F2-alpha receptor (PGF receptor) (PGF2-alpha receptor) (Prostanoid FP receptor)
Gene: PTGFR

Interactor 2: AT2B3 (Q16720)
Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3)
Gene: ATP2B3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 359 Hs			1 1220
+	Hs
		793074 PF2R_HUMAN (1-359): 1.87e-95: 290: 100.00		AT2B2_HUMAN (1-1220): 0: 1231: 81.07
+	Hs
		208456 OX2R_HUMAN (1-358): 4.22e-60: 201: 9.73		AT2B3_HUMAN (1-1220): 0: 1287: 100.00
+	Hs
		781059 OPRX_HUMAN (18-356): 1.18e-59: 198: 15.29		AT2B3_HUMAN (1-1220): 0: 1287: 100.00
+	Hs
		793180 PI2R_HUMAN (25-357): 1.14e-75: 240: 23.46		AT2B2_HUMAN (1-1220): 0: 1231: 81.07
+	Hs
		666307 NK3R_HUMAN (6-339): 1.15e-61: 206: 14.37		AT2B2_HUMAN (1-1220): 0: 1231: 81.07
+	Hs
		208453 OX2R_HUMAN (1-358): 4.22e-60: 201: 9.73		AT2B2_HUMAN (1-1220): 0: 1231: 81.07
+	Hs
		781053 OPRX_HUMAN (18-356): 1.18e-59: 198: 15.29		AT2B2_HUMAN (1-1220): 0: 1231: 81.07
+	Hs
		619208 PE2R3_HUMAN (28-304): 2.16e-65: 213: 35.02		AT2B4_HUMAN (4-1220): 0: 1200: 71.89
+	Hs
		428921 ADRB2_HUMAN (31-355): 1.33e-63: 209: 11.68		AT2B4_HUMAN (4-1220): 0: 1200: 71.89
+	Hs
		619198 NK3R_HUMAN (6-339): 1.15e-61: 206: 14.37		AT2B4_HUMAN (4-1220): 0: 1200: 71.89
+	Hs
		208448 OX2R_HUMAN (1-358): 4.22e-60: 201: 9.73		AT2B4_HUMAN (4-1220): 0: 1200: 71.89
+	Hs
		619206 OPRX_HUMAN (18-356): 1.18e-59: 198: 15.29		AT2B4_HUMAN (4-1220): 0: 1200: 71.89
+	Hs
		619204 APJ_HUMAN (17-349): 3.68e-59: 197: 8.88		AT2B4_HUMAN (4-1220): 0: 1200: 71.89
+	Hs
		619243 OR2G6_HUMAN (3-319): 9.04e-60: 197: 12.58		AT2B4_HUMAN (4-1220): 0: 1200: 71.89
+	Hs
		619282 HCAR1_HUMAN (26-322): 1.42e-11: 66.7: 18.06		AT2B4_HUMAN (4-1220): 0: 1200: 71.89
+	Hs
		530839 NK3R_HUMAN (6-339): 1.15e-61: 206: 14.37		AT1A3_HUMAN (39-1073): 0: 756: 23.47
+	Hs
		392982 ADRB2_HUMAN (31-355): 1.33e-63: 209: 11.68		AT1A1_HUMAN (13-1073): 0: 751: 21.63
+	Hs
		428908 ADRB2_HUMAN (31-355): 1.33e-63: 209: 11.68		AT2A2_HUMAN (50-1075): 0: 750: 24.20
+	Hs
		530844 OPRX_HUMAN (18-356): 1.18e-59: 198: 15.29		AT1A3_HUMAN (39-1073): 0: 756: 23.47
+	Hs
		561517 OPRD_HUMAN (9-350): 9.56e-60: 198: 13.04		AT2A2_HUMAN (50-1075): 0: 750: 24.20