HitPredict

Interactor 1: PE2R3 (P43115)
Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor)
Gene: PTGER3

Interactor 2: TMED8 (Q6PL24)
Protein TMED8
Gene: TMED8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 390 Hs			1 325
+	Hs
		686808 GP183_HUMAN (24-387): 3.73e-60: 200: 15.57		TMED8_HUMAN (1-325): 0: 563: 100.00
+	Hs
		1162797 GPR34_HUMAN (27-381): 5.09e-57: 192: 18.03		TMED8_HUMAN (1-325): 0: 563: 100.00
+	Mm
		1112684 MCHR1_MOUSE (37-357): 1.04e-12: 70.6: 20.99		TMED8_MOUSE (1-325): 0: 539: 85.89
+	Hs
		686818 GP183_HUMAN (24-387): 3.73e-60: 200: 15.57		GCP60_HUMAN (151-324): 2.57e-92: 286: 48.85