HitPredict

Interactor 1: PI2R (P43119)
Prostacyclin receptor (Prostaglandin I2 receptor) (PGI receptor) (PGI2 receptor) (Prostanoid IP receptor)
Gene: PTGIR

Interactor 2: PI2R (P43119)
Prostacyclin receptor (Prostaglandin I2 receptor) (PGI receptor) (PGI2 receptor) (Prostanoid IP receptor)
Gene: PTGIR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 20522800, 15194446
Identification Methods fluorescent resonance energy transfer, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~7tm_1
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
GO:0007187 - G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
and 7 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 386
Hs

1 386
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024