HitPredict

Interactor 1: PI2R (P43119)
Prostacyclin receptor (Prostaglandin I2 receptor) (PGI receptor) (PGI2 receptor) (Prostanoid IP receptor)
Gene: PTGIR

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	22889411
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 386 Hs			1 728
+	Hs
		626691 ADA1D_HUMAN (16-383): 2.1e-63: 214: 14.95		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		793194 PI2R_HUMAN (1-386): 1.72e-74: 237: 100.00		NHRF4_HUMAN (213-723): 3.81e-48: 181: 16.22
+	Hs
		1029371 PD2R_HUMAN (40-301): 1.87e-94: 288: 43.82		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52
+	Hs
		626682 ADA1D_HUMAN (16-383): 2.1e-63: 214: 14.95		DLG1_HUMAN (354-728): 3.16e-29: 126: 16.15
+	Rn
		495779 ADRB2_RAT (5-375): 3.49e-74: 238: 12.53		DLG4_RAT (267-582): 6.83e-21: 99.8: 16.09
+	Rn
		677498 SSR4_RAT (19-373): 6.63e-72: 231: 15.92		DLG4_RAT (267-582): 6.83e-21: 99.8: 16.09
+	Mm
		830267 SSR4_MOUSE (19-373): 5.83e-71: 229: 17.04		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40
+	Mm
		578603 ADRB2_MOUSE (5-375): 3.24e-74: 238: 12.53		MAGI3_MOUSE (320-722): 1.27e-16: 86.7: 12.84
+	Hs
		429068 ADRB2_HUMAN (5-376): 1.54e-72: 233: 14.29		MAGI3_HUMAN (258-722): 6.12e-18: 90.9: 11.75
+	Hs
		441650 ADRB1_HUMAN (2-380): 3.48e-66: 219: 13.65		DLG4_HUMAN (581-725): 3.01e-21: 100: 22.22
+	Mm
		676818 SSR2_MOUSE (2-340): 3.76e-67: 218: 13.95		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40
+	Hs
		600726 DRD1_HUMAN (30-371): 1.46e-65: 216: 16.58		DLG4_HUMAN (581-725): 3.01e-21: 100: 22.22
+	Mm
		676812 SSR1_MOUSE (12-308): 7.01e-65: 213: 14.38		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40
+	Hs
		441654 ADRB1_HUMAN (2-380): 3.48e-66: 219: 13.65		MAGI2_HUMAN (151-509): 8.26e-19: 93.6: 11.36
+	Hs
		441653 ADRB1_HUMAN (2-380): 3.48e-66: 219: 13.65		MAGI3_HUMAN (258-722): 6.12e-18: 90.9: 11.75
+	Hs
		793185 PI2R_HUMAN (1-386): 1.72e-74: 237: 100.00		NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56
+	Mm
		830268 SSR4_MOUSE (19-373): 5.83e-71: 229: 17.04		DLG2_MOUSE (352-500): 5.83e-11: 68.2: 17.95
+	Hs
		626687 ADA1D_HUMAN (16-383): 2.1e-63: 214: 14.95		SCRIB_HUMAN (265-624): 2.64e-15: 82.4: 13.52
+	Hs
		722923 SSR5_HUMAN (24-336): 1.84e-66: 216: 17.61		NHRF3_HUMAN (133-355): 1.14e-11: 69.7: 12.56
+	Mm
		676813 SSR1_MOUSE (12-308): 7.01e-65: 213: 14.38		DLG2_MOUSE (352-500): 5.83e-11: 68.2: 17.95