HitPredict

Interactor 1: PI2R (P43119)
Prostacyclin receptor (Prostaglandin I2 receptor) (PGI receptor) (PGI2 receptor) (Prostanoid IP receptor)
Gene: PTGIR

Interactor 2: S12A7 (Q9Y666)
Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4)
Gene: SLC12A7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 386 Hs			1 1083
+	Hs
		793221 PI2R_HUMAN (1-386): 1.72e-74: 237: 100.00		S12A6_HUMAN (14-1083): 0: 1102: 69.47
+	Hs
		825761 MTR1B_HUMAN (7-336): 2.38e-58: 195: 20.48		S12A4_HUMAN (1-1083): 0: 1105: 69.48
+	Hs
		621360 FSHR_HUMAN (25-350): 1.82e-12: 70.9: 17.73		S12A7_HUMAN (1-1083): 0: 1174: 100.00
+	Hs
		793176 PI2R_HUMAN (1-386): 1.72e-74: 237: 100.00		S12A2_HUMAN (25-1083): 0: 746: 20.65
+	Hs
		723286 APJ_HUMAN (3-357): 6.16e-64: 210: 15.20		S12A2_HUMAN (25-1083): 0: 746: 20.65
+	Hs
		793211 PI2R_HUMAN (1-386): 1.72e-74: 237: 100.00		S12A9_HUMAN (116-911): 1.32e-167: 518: 24.88
+	Hs
		793175 PI2R_HUMAN (1-386): 1.72e-74: 237: 100.00		CTR2_HUMAN (160-603): 3.52e-94: 316: 16.18
+	Hs
		208469 OX2R_HUMAN (11-369): 2.28e-63: 210: 13.82		CTR3_HUMAN (160-603): 3.59e-81: 279: 15.02