Interactor 1: MUC18 (P43121)
Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146)
Gene: MCAM

Interactor 2: CD166 (Q13740)
CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166)
Gene: ALCAM

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 38117590
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C2-set_2~C2-set_2, C2-set_2~Ig_3, Ig_3~Ig_3, C2-set_2~V-set, Ig_3~V-set
Common GO terms GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007155 - cell adhesion
GO:0009897 - external side of plasma membrane
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 646
Hs

1 583
+ Hs
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+ Ce
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+ Mm
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+ Dr

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024