HitPredict

Interactor 1: MUC18 (P43121)
Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146)
Gene: MCAM

Interactor 2: KS6A1 (Q15418)
Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)
Gene: RPS6KA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	38117590
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~V-set
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 735
+	Hs
		270448 ROBO2_HUMAN (1-646): 1.16e-96: 325: 14.69		KS6A5_HUMAN (46-730): 0: 706: 41.42
+	Hs
		647841 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		MARK3_HUMAN (408-695): 1.9e-108: 348: 28.48
+	Hs
		793320 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		KS6A2_HUMAN (2-321): 2.57e-98: 321: 23.80
+	Hs
		530144 NCAM1_HUMAN (11-644): 1.38e-81: 277: 15.63		KAPCA_HUMAN (414-712): 3.66e-114: 350: 29.71
+	Hs
		1071679 KIRR1_HUMAN (240-644): 1.88e-28: 123: 15.77		KS6A2_HUMAN (2-321): 2.57e-98: 321: 23.80