HitPredict

Interactor 1: MUC18 (P43121)
Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146)
Gene: MCAM

Interactor 2: VPP1 (Q93050)
V-type proton ATPase 116 kDa subunit a 1 (V-ATPase 116 kDa subunit a 1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)
Gene: ATP6V0A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 837
+	Hs
		842272 BCAM_HUMAN (24-521): 3.96e-121: 375: 29.00		VPP1_HUMAN (1-837): 0: 1344: 100.00
+	Hs
		793539 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		VPP2_HUMAN (1-830): 0: 1177: 53.53
+	Hs
		842280 BCAM_HUMAN (24-521): 3.96e-121: 375: 29.00		VPP2_HUMAN (1-830): 0: 1177: 53.53
+	Dm
		1213066 Q9BN17_DROME (25-345): 8.9e-21: 99.6: 16.42		Q8IML5_DROME (1-832): 0: 1163: 61.07