HitPredict

Interactor 1: MUC18 (P43121)
Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146)
Gene: MCAM

Interactor 2: FRMD6 (Q96NE9)
FERM domain-containing protein 6 (Willin)
Gene: FRMD6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38117590
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 646 Hs			1 622
+	Hs
		793292 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		PTN13_HUMAN (14-401): 8.49e-120: 394: 24.49
+	Hs
		793480 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		E41L5_HUMAN (5-598): 2.32e-127: 393: 14.73
+	Hs
		793472 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		E41L1_HUMAN (18-573): 2.35e-114: 364: 15.00
+	Hs
		793536 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		E41L3_HUMAN (13-569): 1.1e-111: 361: 13.81
+	Hs
		546964 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		EZRI_HUMAN (12-593): 3.93e-115: 357: 16.10
+	Hs
		719677 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RADI_HUMAN (12-593): 4.76e-115: 357: 15.33
+	Hs
		505577 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		EPB41_HUMAN (14-572): 1.19e-110: 353: 14.83
+	Hs
		719405 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		MERL_HUMAN (9-594): 1.95e-113: 353: 15.41
+	Hs
		640060 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		MOES_HUMAN (12-595): 1.26e-110: 345: 15.20
+	Hs
		204628 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		E41L2_HUMAN (13-545): 1.19e-105: 343: 12.70
+	Hs
		640221 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		PTN3_HUMAN (5-547): 9.8e-102: 331: 14.19
+	Hs
		793325 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		PTN14_HUMAN (20-336): 1.44e-73: 258: 19.75
+	Hs
		547134 KIRR3_HUMAN (6-625): 1.84e-82: 278: 18.22		EZRI_HUMAN (12-593): 3.93e-115: 357: 16.10
+	Hs
		719746 KIRR3_HUMAN (6-625): 1.84e-82: 278: 18.22		RADI_HUMAN (12-593): 4.76e-115: 357: 15.33
+	Mm
		1206834 PTK7_MOUSE (141-613): 9.65e-54: 201: 15.07		E41L3_MOUSE (13-572): 2.06e-116: 370: 13.54
+	Dm
		802983 Q9BN17_DROME (25-345): 8.9e-21: 99.6: 16.42		MOEH_DROME (25-404): 2.32e-113: 352: 22.34
+	Hs
		719447 PGBM_HUMAN (222-493): 1.42e-10: 67.1: 9.46		MERL_HUMAN (9-594): 1.95e-113: 353: 15.41
+	Hs
		640132 TITIN_HUMAN (50-634): 4.44e-11: 68.6: 11.22		MOES_HUMAN (12-595): 1.26e-110: 345: 15.20
+	Dm
		1098337 Q9VQW7_DROME (25-345): 8.83e-21: 99.6: 16.42		MERH_DROME (13-381): 1.87e-85: 281: 18.18
+	Dm
		991234 Q9VQW7_DROME (25-345): 8.83e-21: 99.6: 16.42		EXPA_DROME (26-166): 9.53e-15: 80.1: 32.65