HitPredict

Interactor 1: A0A087WZU1 (A0A087WZU1)
protein-tyrosine-phosphatase (EC 3.1.3.48)
Gene: PTPRQ

Interactor 2: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2299 Hs			1 541
+	Hs
		791 A0A087WZU1_HUMAN (1-2299): 0: 1513: 100.00		NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78
+	Hs
		786 A0A087WZU1_HUMAN (1-2299): 0: 1513: 100.00		NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89
+	Rn
		88577 D3ZDA6_RAT (8-1427): 4.47e-141: 492: 17.73		SHAN2_RAT (43-147): 1.03e-28: 123: 38.10
+	Rn
		88571 D3ZDA6_RAT (8-1427): 4.47e-141: 492: 17.73		MAGI2_RAT (45-372): 6.38e-17: 86.5: 14.79
+	Hs
		1123250 SDK2_HUMAN (8-1427): 6.02e-140: 489: 17.42		NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70
+	Rn
		88576 D3ZDA6_RAT (8-1427): 4.47e-141: 492: 17.73		MAGI3_RAT (15-356): 6.33e-14: 77.3: 16.34
+	Hs
		234545 DSCAM_HUMAN (8-872): 5.64e-67: 254: 13.66		MAGI2_HUMAN (45-372): 3.17e-16: 84.6: 14.79
+	Hs
		234530 DSCAM_HUMAN (8-872): 5.64e-67: 254: 13.66		MAGI3_HUMAN (19-429): 6.34e-14: 77.3: 15.39
+	Mm
		82787 PTPRZ_MOUSE (2027-2268): 4.67e-23: 110: 30.92		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Rn
		94280 F1LXJ9_RAT (7-509): 4.79e-17: 90.5: 11.61		MAGI2_RAT (45-372): 6.38e-17: 86.5: 14.79
+	Hs
		616920 PTPRB_HUMAN (20-380): 1.63e-10: 68.9: 14.48		MAGI3_HUMAN (19-429): 6.34e-14: 77.3: 15.39