HitPredict

Interactor 1: MSH2 (P43246)
DNA mismatch repair protein Msh2 (hMSH2) (MutS protein homolog 2)
Gene: MSH2

Interactor 2: RFA4 (Q13156)
Replication protein A 30 kDa subunit (RP-A p30) (Replication factor A protein 4) (RF-A protein 4)
Gene: RPA4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	37827155, 19468048
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 934 Hs			1 261
+	Hs
		552147 MSH2_HUMAN (1-934): 0: 1120: 100.00		RFA2_HUMAN (1-261): 7.63e-105: 306: 42.03
+	Hs
		552296 MSH6_HUMAN (7-855): 0: 787: 22.11		RFA2_HUMAN (1-261): 7.63e-105: 306: 42.03
+	Hs
		594189 MSH3_HUMAN (6-861): 0: 721: 23.13		RFA4_HUMAN (1-261): 1.82e-106: 310: 100.00
+	Hs
		551929 MSH3_HUMAN (6-861): 0: 721: 23.13		RFA2_HUMAN (1-261): 7.63e-105: 306: 42.03
+	Sc
		644772 MSH6_YEAST (7-862): 0: 702: 22.62		RFA2_YEAST (6-257): 2.32e-67: 211: 23.38