Interactor 1: MSH2 (P43246)
DNA mismatch repair protein Msh2 (hMSH2) (MutS protein homolog 2)
Gene: MSH2

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.721

The method score is based on:

Property Details
Experiments 19596235, 31495888, 32398829, 37071664, 22902628
Identification Methods two hybrid, affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 934
Hs

1 1834
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024