HitPredict

Interactor 1: MSH2 (P43246)
DNA mismatch repair protein Msh2 (hMSH2) (MutS protein homolog 2)
Gene: MSH2

Interactor 2: SMRCD (Q9H4L7)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) (ATP-dependent helicase 1) (hHEL1)
Gene: SMARCAD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.743

The method score is based on:

Property Details
Experiments 31843968, 33961781, 35784486, 34591612, 37140056, 18675275, 21549307
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 2 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 934
Hs

1 1026
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024