HitPredict

Interactor 1: MSH2 (P43246)
DNA mismatch repair protein Msh2 (hMSH2) (MutS protein homolog 2)
Gene: MSH2

Interactor 2: EXO1 (Q9UQ84)
Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI)
Gene: EXO1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.749

The method score is based on:

Property Details
Experiments 11427529, 37140056, 33961781, 10856833, 9788596, 19015241, 22222486, 12414623
Identification Methods pull down, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
and 3 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 934
Hs

1 846
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024