HitPredict

Interactor 1: H11 (P43275)
Histone H1.1 (H1 VAR.3) (Histone H1a) (H1a)
Gene: H1-1

Interactor 2: CDK6 (Q64261)
Cyclin-dependent kinase 6 (EC 2.7.11.22) (CR2 protein kinase) (CRK2) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)
Gene: CDK6

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12007403
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 213 Mm			1 326
+	Rn
		413197 H1T_RAT (1-201): 3.81e-36: 127: 49.25		Q6P751_RAT (10-311): 1.59e-146: 415: 47.06
+	Rn
		88903 H11_RAT (1-124): 5.9e-25: 99: 92.74		Q6P751_RAT (10-311): 1.59e-146: 415: 47.06
+	Hs
		559328 H13_HUMAN (1-162): 1.31e-23: 95.5: 59.28		CDK2_HUMAN (10-311): 4.32e-147: 417: 47.39
+	Hs
		558990 H15_HUMAN (1-117): 1.41e-20: 87.8: 68.64		CDK2_HUMAN (10-311): 4.32e-147: 417: 47.39
+	Mm
		794656 H15_MOUSE (1-196): 9.52e-22: 90.9: 60.29		CDK2_MOUSE (10-311): 5.54e-138: 396: 40.68
+	Mm
		794643 H11_MOUSE (1-181): 1.43e-19: 84.7: 100.00		CDK2_MOUSE (10-311): 5.54e-138: 396: 40.68
+	Mm
		550489 H12_MOUSE (32-117): 4.78e-17: 78.2: 80.23		CDK2_MOUSE (10-311): 5.54e-138: 396: 40.68
+	Rn
		88899 H11_RAT (1-124): 5.9e-25: 99: 92.74		CDK1_RAT (10-305): 1.84e-130: 375: 45.18
+	Hs
		414717 H13_HUMAN (1-162): 1.31e-23: 95.5: 59.28		CDK1_HUMAN (10-305): 2.69e-130: 375: 45.52
+	Hs
		414716 H15_HUMAN (1-117): 1.41e-20: 87.8: 68.64		CDK1_HUMAN (10-305): 2.69e-130: 375: 45.52
+	Hs
		515324 H13_HUMAN (1-162): 1.31e-23: 95.5: 59.28		CDK4_HUMAN (9-300): 4.5e-126: 364: 70.51
+	Mm
		509472 H11_MOUSE (1-181): 1.43e-19: 84.7: 100.00		CDK1_MOUSE (10-305): 1.33e-129: 373: 45.18
+	Mm
		673226 H15_MOUSE (1-196): 9.52e-22: 90.9: 60.29		CDK4_MOUSE (12-300): 5.54e-126: 364: 69.52
+	Mm
		509461 H12_MOUSE (32-117): 4.78e-17: 78.2: 80.23		CDK1_MOUSE (10-305): 1.33e-129: 373: 45.18
+	Mm
		673225 H11_MOUSE (1-181): 1.43e-19: 84.7: 100.00		CDK4_MOUSE (12-300): 5.54e-126: 364: 69.52
+	Mm
		550487 H12_MOUSE (32-117): 4.78e-17: 78.2: 80.23		CDK4_MOUSE (12-300): 5.54e-126: 364: 69.52
+	Hs
		489003 H14_HUMAN (1-117): 1.45e-21: 90.1: 73.50		CDK5_HUMAN (11-303): 3.4e-116: 339: 45.64
+	Hs
		559065 H15_HUMAN (1-117): 1.41e-20: 87.8: 68.64		CDK5_HUMAN (11-303): 3.4e-116: 339: 45.64
+	Hs
		559654 H12_HUMAN (1-180): 1.1e-20: 87.8: 57.78		CDK5_HUMAN (11-303): 3.4e-116: 339: 45.64
+	Mm
		794639 H11_MOUSE (1-181): 1.43e-19: 84.7: 100.00		CDK5_MOUSE (11-303): 5.04e-116: 338: 45.64