HitPredict

Interactor 1: PIP21 (P43286)
Aquaporin PIP2-1 (Plasma membrane intrinsic protein 2-1) (AtPIP2;1) (Plasma membrane intrinsic protein 2a) (PIP2a)
Gene: PIP2-1

Interactor 2: PIP22 (P43287)
Aquaporin PIP2-2 (Plasma membrane intrinsic protein 2-2) (AtPIP2;2) (Plasma membrane intrinsic protein 2b) (PIP2b) (TMP2b)
Gene: PIP2-2

Species: Arabidopsis thaliana

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.757

Property	Details
Experiments	21423366, 27609422
Identification Methods	protein complementation assay, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	MIP~MIP
Common GO terms	GO:0003729 - mRNA binding GO:0005886 - plasma membrane GO:0006833 - water transport GO:0009414 - response to water deprivation GO:0009506 - plasmodesma and 1 others more... GO:0015250 - water channel activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 287 At			1 285
+	At
		673350 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP23_ARATH (1-285): 2.61e-106: 312: 96.84
+	At
		794679 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP21_ARATH (1-285): 4.27e-105: 308: 93.38
+	At
		794900 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP25_ARATH (1-285): 3.75e-103: 303: 78.67
+	At
		794919 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP26_ARATH (1-284): 4.01e-102: 301: 77.90
+	At
		794799 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP24_ARATH (1-281): 2.96e-101: 299: 84.10
+	At
		794706 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP27_ARATH (1-283): 2.97e-100: 296: 75.00
+	At
		794924 PIP22_ARATH (1-287): 4.13e-103: 303: 93.03		PIP27_ARATH (1-283): 2.97e-100: 296: 75.00
+	At
		673352 PIP23_ARATH (1-287): 1.22e-100: 297: 90.94		PIP27_ARATH (1-283): 2.97e-100: 296: 75.00
+	At
		794727 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP14_ARATH (8-277): 6.11e-97: 288: 71.85
+	At
		794929 PIP22_ARATH (1-287): 4.13e-103: 303: 93.03		PIP14_ARATH (8-277): 6.11e-97: 288: 71.85
+	At
		794711 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP12_ARATH (7-277): 7.5e-96: 285: 70.85
+	At
		794925 PIP22_ARATH (1-287): 4.13e-103: 303: 93.03		PIP12_ARATH (7-277): 7.5e-96: 285: 70.85
+	At
		673353 PIP23_ARATH (1-287): 1.22e-100: 297: 90.94		PIP12_ARATH (7-277): 7.5e-96: 285: 70.85
+	At
		794704 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP11_ARATH (7-277): 4.16e-91: 273: 71.22
+	At
		794713 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP13_ARATH (7-277): 8.72e-91: 272: 72.33
+	At
		794754 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP15_ARATH (8-276): 1.24e-90: 272: 71.38
+	At
		794926 PIP22_ARATH (1-287): 4.13e-103: 303: 93.03		PIP13_ARATH (7-277): 8.72e-91: 272: 72.33
+	At
		794930 PIP22_ARATH (1-287): 4.13e-103: 303: 93.03		PIP15_ARATH (8-276): 1.24e-90: 272: 71.38
+	At
		673351 PIP23_ARATH (1-287): 1.22e-100: 297: 90.94		PIP11_ARATH (7-277): 4.16e-91: 273: 71.22