HitPredict

Interactor 1: PIP21 (P43286)
Aquaporin PIP2-1 (Plasma membrane intrinsic protein 2-1) (AtPIP2;1) (Plasma membrane intrinsic protein 2a) (PIP2a)
Gene: PIP2-1

Interactor 2: PIP14 (Q39196)
Probable aquaporin PIP1-4 (Plasma membrane intrinsic protein 1-4) (AtPIP1;4) (Transmembrane protein C) (TMP-C)
Gene: PIP1.4

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	24833385, 27609422
Identification Methods	protein complementation assay, affinity chromatography technology, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	MIP~MIP
Common GO terms	GO:0005886 - plasma membrane GO:0006833 - water transport GO:0009414 - response to water deprivation GO:0009506 - plasmodesma GO:0015250 - water channel activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 287 At			1 287
+	At
		794929 PIP22_ARATH (1-287): 4.13e-103: 303: 93.03		PIP14_ARATH (1-287): 1.18e-115: 335: 100.00
+	At
		794711 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP12_ARATH (1-287): 8.18e-113: 328: 93.73
+	At
		794925 PIP22_ARATH (1-287): 4.13e-103: 303: 93.03		PIP12_ARATH (1-287): 8.18e-113: 328: 93.73
+	At
		794754 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP15_ARATH (1-287): 2.43e-109: 320: 93.73
+	At
		794930 PIP22_ARATH (1-287): 4.13e-103: 303: 93.03		PIP15_ARATH (1-287): 2.43e-109: 320: 93.73
+	At
		794704 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP11_ARATH (1-287): 7.1e-108: 316: 94.43
+	At
		794713 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP13_ARATH (1-287): 1.32e-107: 315: 96.86
+	At
		794926 PIP22_ARATH (1-287): 4.13e-103: 303: 93.03		PIP13_ARATH (1-287): 1.32e-107: 315: 96.86
+	At
		673351 PIP23_ARATH (1-287): 1.22e-100: 297: 90.94		PIP11_ARATH (1-287): 7.1e-108: 316: 94.43
+	At
		794706 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP27_ARATH (18-286): 5.35e-101: 298: 73.23
+	At
		794924 PIP22_ARATH (1-287): 4.13e-103: 303: 93.03		PIP27_ARATH (18-286): 5.35e-101: 298: 73.23
+	At
		794680 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP22_ARATH (19-286): 9.35e-100: 295: 70.80
+	At
		794799 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP24_ARATH (17-286): 1.3e-98: 292: 67.75
+	At
		794900 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP25_ARATH (18-286): 1.86e-98: 292: 69.09
+	At
		673352 PIP23_ARATH (1-287): 1.22e-100: 297: 90.94		PIP27_ARATH (18-286): 5.35e-101: 298: 73.23
+	At
		794919 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP26_ARATH (18-285): 6.89e-98: 290: 68.61
+	At
		673350 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP23_ARATH (19-286): 5.96e-97: 288: 69.71
+	At
		794679 PIP21_ARATH (1-287): 1.12e-103: 305: 100.00		PIP21_ARATH (25-286): 4.25e-97: 288: 72.76