Interactor 1: RAD52 (P43351)
DNA repair protein RAD52 homolog
Gene: RAD52
Interactor 2: WRN (Q14191)
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 5.6.2.4) (DNA 3'-5' helicase WRN)]
Gene: WRN
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.71 | 0.55 | 0.628 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17118963, 12750383 |
| Identification Methods | pull down, two hybrid, far western blotting, affinity chromatography technology, fluorescent resonance energy transfer, coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000724 - double-strand break repair via homologous recombination GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006302 - double-strand break repair |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
