HitPredict

Interactor 1: MAGA1 (P43355)
Melanoma-associated antigen 1 (Antigen MZ2-E) (Cancer/testis antigen 1.1) (CT1.1) (MAGE-1 antigen)
Gene: MAGEA1

Interactor 2: MAGB6 (Q8N7X4)
Melanoma-associated antigen B6 (Cancer/testis antigen 3.4) (CT3.4) (MAGE-B6 antigen)
Gene: MAGEB6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	MAGE~MAGE
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 309 Hs			1 407
+	Hs
		796255 MAGAB_HUMAN (1-309): 4.46e-150: 429: 59.25		MAGAB_HUMAN (15-400): 4.43e-148: 428: 31.35
+	Hs
		795807 MAGA4_HUMAN (1-297): 1.68e-144: 411: 74.43		MAGAA_HUMAN (80-407): 2.61e-136: 396: 35.31
+	Hs
		795716 MAGA3_HUMAN (1-307): 1.09e-144: 411: 66.56		MAGA8_HUMAN (81-399): 1.86e-135: 392: 34.17
+	Hs
		795805 MAGA4_HUMAN (1-297): 1.68e-144: 411: 74.43		MAGA8_HUMAN (81-399): 1.86e-135: 392: 34.17
+	Hs
		795849 MAGAB_HUMAN (1-309): 4.46e-150: 429: 59.25		MAGA6_HUMAN (79-400): 1.42e-122: 359: 31.37
+	Hs
		796241 MAGAA_HUMAN (1-308): 2.27e-143: 410: 50.00		MAGBA_HUMAN (86-397): 7.4e-129: 376: 36.22
+	Hs
		795806 MAGA4_HUMAN (1-297): 1.68e-144: 411: 74.43		MAGA9_HUMAN (79-400): 2.74e-128: 373: 33.85
+	Hs
		796054 MAGAA_HUMAN (1-308): 2.27e-143: 410: 50.00		MAGA9_HUMAN (79-400): 2.74e-128: 373: 33.85
+	Hs
		1297544 MAGBI_HUMAN (1-306): 1.2e-141: 404: 42.63		MAGBA_HUMAN (86-397): 7.4e-129: 376: 36.22
+	Hs
		795611 MAGA1_HUMAN (1-296): 9.64e-141: 401: 100.00		MAGA9_HUMAN (79-400): 2.74e-128: 373: 33.85
+	Hs
		56489 MAGA4_HUMAN (1-297): 1.68e-144: 411: 74.43		MAGBG_HUMAN (88-406): 1.94e-123: 361: 37.54
+	Hs
		795715 MAGA3_HUMAN (1-307): 1.09e-144: 411: 66.56		MAGA6_HUMAN (79-400): 1.42e-122: 359: 31.37
+	Hs
		795688 MAGA3_HUMAN (1-307): 1.09e-144: 411: 66.56		MAGA2_HUMAN (79-400): 2.28e-120: 353: 31.06
+	Hs
		180537 MAGA3_HUMAN (1-307): 1.09e-144: 411: 66.56		MAGB4_HUMAN (1-93): 8.86e-18: 85.6: 52.13
+	Hs
		180538 MAGA8_HUMAN (1-306): 6.35e-141: 402: 66.77		MAGB4_HUMAN (1-93): 8.86e-18: 85.6: 52.13
+	Hs
		180536 MAGA1_HUMAN (1-296): 9.64e-141: 401: 100.00		MAGB4_HUMAN (1-93): 8.86e-18: 85.6: 52.13
+	Hs
		180521 MAGA1_HUMAN (1-296): 9.64e-141: 401: 100.00		MAGB3_HUMAN (1-107): 1.16e-16: 82.6: 37.04