HitPredict

Interactor 1: MAGA4 (P43358)
Melanoma-associated antigen 4 (Cancer/testis antigen 1.4) (CT1.4) (MAGE-4 antigen) (MAGE-41 antigen) (MAGE-X2 antigen)
Gene: MAGEA4

Interactor 2: MAGAA (P43363)
Melanoma-associated antigen 10 (Cancer/testis antigen 1.10) (CT1.10) (MAGE-10 antigen)
Gene: MAGEA10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	MAGE~MAGE
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0042826 - histone deacetylase binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 369
+	Hs
		796255 MAGAB_HUMAN (1-317): 3.14e-152: 435: 62.19		MAGAB_HUMAN (1-339): 1.55e-153: 440: 53.39
+	Hs
		795805 MAGA4_HUMAN (1-317): 1.37e-153: 434: 100.00		MAGA8_HUMAN (1-338): 6.75e-147: 419: 55.33
+	Hs
		795716 MAGA3_HUMAN (1-315): 6.17e-148: 419: 68.25		MAGA8_HUMAN (1-338): 6.75e-147: 419: 55.33
+	Hs
		56489 MAGA4_HUMAN (1-317): 1.37e-153: 434: 100.00		MAGBG_HUMAN (1-345): 1.95e-139: 401: 45.95
+	Hs
		795849 MAGAB_HUMAN (1-317): 3.14e-152: 435: 62.19		MAGA6_HUMAN (1-339): 1.08e-137: 396: 48.97
+	Hs
		795806 MAGA4_HUMAN (1-317): 1.37e-153: 434: 100.00		MAGA9_HUMAN (1-339): 7.81e-136: 391: 48.38
+	Hs
		180537 MAGA3_HUMAN (1-315): 6.17e-148: 419: 68.25		MAGB4_HUMAN (1-354): 4.63e-139: 401: 45.51
+	Hs
		795715 MAGA3_HUMAN (1-315): 6.17e-148: 419: 68.25		MAGA6_HUMAN (1-339): 1.08e-137: 396: 48.97
+	Hs
		180538 MAGA8_HUMAN (1-314): 2.78e-144: 411: 71.61		MAGB4_HUMAN (1-354): 4.63e-139: 401: 45.51
+	Hs
		795688 MAGA3_HUMAN (1-315): 6.17e-148: 419: 68.25		MAGA2_HUMAN (1-339): 2.43e-135: 390: 48.97
+	Hs
		796054 MAGAA_HUMAN (1-316): 2.48e-143: 410: 50.88		MAGA9_HUMAN (1-339): 7.81e-136: 391: 48.38
+	Hs
		1297544 MAGBI_HUMAN (1-314): 2.74e-144: 411: 42.99		MAGBA_HUMAN (1-358): 4.13e-132: 383: 44.41
+	Hs
		796241 MAGAA_HUMAN (1-316): 2.48e-143: 410: 50.88		MAGBA_HUMAN (1-358): 4.13e-132: 383: 44.41
+	Hs
		180521 MAGB3_HUMAN (1-317): 7.7e-139: 398: 40.94		MAGA1_HUMAN (1-328): 1.98e-132: 382: 51.83