HitPredict

Interactor 1: ZAP70 (P43403)
Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)
Gene: ZAP70

Interactor 2: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15084271
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 619 Hs			1 451
+	Hs
		796477 ZAP70_HUMAN (1-619): 0: 641: 100.00		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428077 ZAP70_HUMAN (1-619): 0: 641: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		796597 KSYK_HUMAN (1-600): 0: 554: 53.58		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428078 KSYK_HUMAN (1-600): 0: 554: 53.58		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		665203 EPHA2_HUMAN (20-614): 3.34e-152: 465: 22.71		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		411549 LCK_HUMAN (58-608): 4.13e-159: 467: 26.79		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		411668 LCK_HUMAN (58-608): 4.13e-159: 467: 26.79		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		665575 EPHB2_HUMAN (70-611): 1.05e-144: 447: 24.29		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		522895 SRC_HUMAN (73-607): 2.65e-149: 443: 25.14		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		522894 SRC_HUMAN (73-607): 2.65e-149: 443: 25.14		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		933452 EPHA7_HUMAN (70-606): 2.14e-141: 437: 23.53		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		1072528 EPHA7_HUMAN (70-606): 2.14e-141: 437: 23.53		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		427991 SRC_HUMAN (73-607): 2.65e-149: 443: 25.14		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		428222 EPHA7_HUMAN (70-606): 2.14e-141: 437: 23.53		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		428109 EPHA4_HUMAN (72-616): 4.07e-141: 436: 24.65		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		428098 BLK_HUMAN (77-608): 1.4e-146: 435: 26.11		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		782771 CSK_HUMAN (90-599): 3.17e-140: 417: 27.41		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		872631 EPHA4_HUMAN (72-616): 4.07e-141: 436: 24.65		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		433849 LYN_HUMAN (75-608): 2.44e-137: 412: 24.72		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428198 PTK6_HUMAN (129-596): 3.44e-136: 406: 27.94		TBB5_HUMAN (1-439): 0: 699: 41.23