HitPredict

Interactor 1: ZAP70 (P43404)
Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)
Gene: ZAP70

Interactor 2: LY9 (Q01965)
T-lymphocyte surface antigen Ly-9 (Cell surface molecule Ly-9) (Lymphocyte antigen 9) (SLAM family member 3) (SLAMF3) (Signaling lymphocytic activation molecule 3) (CD antigen CD229)
Gene: LY9

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	24584089
Identification Methods	affinity chromatography technology
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045087 - innate immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 618 Mm			1 654
+	Hs
		530151 EPHA3_HUMAN (54-614): 1.02e-155: 474: 23.89		NCAM1_HUMAN (31-619): 1.58e-57: 210: 12.30
+	Hs
		770260 KSYK_HUMAN (1-598): 0: 543: 54.05		CEAM3_HUMAN (13-153): 8.38e-36: 137: 16.55
+	Hs
		434019 LYN_HUMAN (75-607): 1.41e-154: 456: 25.83		ROBO2_HUMAN (3-548): 9.85e-60: 219: 13.53
+	Hs
		789096 ABL2_HUMAN (103-616): 1.55e-149: 463: 27.66		SLAF5_HUMAN (32-244): 3.94e-60: 206: 31.80
+	Hs
		590606 KSYK_HUMAN (1-598): 0: 543: 54.05		CD22_HUMAN (192-641): 3.05e-24: 110: 11.09
+	Hs
		665402 EPHA3_HUMAN (54-614): 1.02e-155: 474: 23.89		CEA21_HUMAN (238-497): 2.26e-48: 173: 20.30
+	Hs
		665394 EPHA3_HUMAN (54-614): 1.02e-155: 474: 23.89		SLAF1_HUMAN (232-535): 5.87e-46: 168: 16.56
+	Hs
		872657 EPHA4_HUMAN (54-612): 1.06e-150: 461: 24.04		CEA21_HUMAN (238-497): 2.26e-48: 173: 20.30
+	Hs
		454828 FGR_HUMAN (109-608): 1.92e-146: 435: 25.15		SLAF1_HUMAN (232-535): 5.87e-46: 168: 16.56
+	Hs
		434081 LYN_HUMAN (75-607): 1.41e-154: 456: 25.83		TUTLB_HUMAN (3-498): 8.42e-35: 144: 12.65
+	Hs
		411818 LCK_HUMAN (58-607): 3.03e-144: 429: 25.09		SLAF6_HUMAN (32-266): 5.22e-47: 170: 26.75
+	Hs
		434111 LYN_HUMAN (75-607): 1.41e-154: 456: 25.83		ROBO1_HUMAN (3-343): 4.52e-33: 138: 16.33
+	Dm
		219802 ABL_DROME (105-596): 9.83e-146: 462: 28.27		O44924_DROME (3-343): 3.31e-28: 123: 12.36
+	Hs
		789014 TEC_HUMAN (122-595): 4.16e-143: 430: 27.74		TUTLB_HUMAN (3-498): 8.42e-35: 144: 12.65
+	Hs
		433507 YES_HUMAN (45-609): 9.99e-143: 427: 21.88		TUTLB_HUMAN (3-498): 8.42e-35: 144: 12.65
+	Hs
		433569 LYN_HUMAN (75-607): 1.41e-154: 456: 25.83		CD22_HUMAN (192-641): 3.05e-24: 110: 11.09
+	Hs
		433804 LYN_HUMAN (75-607): 1.41e-154: 456: 25.83		SDK2_HUMAN (1-635): 3.13e-13: 75.5: 12.57
+	Hs
		411561 LCK_HUMAN (58-607): 3.03e-144: 429: 25.09		CD48_HUMAN (246-469): 1.27e-23: 102: 20.71
+	Hs
		411547 LCK_HUMAN (58-607): 3.03e-144: 429: 25.09		CD2_HUMAN (34-233): 2.14e-10: 64.6: 18.84
+	Hs
		416917 ITK_HUMAN (78-598): 3.23e-142: 428: 25.28		CD2_HUMAN (34-233): 2.14e-10: 64.6: 18.84