HitPredict

Interactor 1: KSYK (P43405)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Gene: SYK

Interactor 2: GRASP (Q7Z6J2)
Protein TAMALIN (General receptor for phosphoinositides 1-associated scaffold protein) (GRP1-associated scaffold protein)
Gene: TAMALIN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15173175
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 635 Hs			1 395
+	Hs
		153892 KSYK_HUMAN (1-635): 0: 589: 100.00		NHRF1_HUMAN (92-255): 2.27e-21: 96.2: 22.09
+	Hs
		523041 SRC_HUMAN (4-371): 2.15e-70: 239: 15.46		GRASP_HUMAN (1-395): 2.85e-89: 276: 100.00
+	Hs
		412243 FYN_HUMAN (4-201): 3.14e-69: 236: 22.03		GRASP_HUMAN (1-395): 2.85e-89: 276: 100.00
+	Hs
		153901 EPHB1_HUMAN (218-632): 1.32e-117: 375: 27.87		NHRF1_HUMAN (92-255): 2.27e-21: 96.2: 22.09
+	Hs
		153863 FGFR1_HUMAN (179-635): 7.43e-116: 366: 26.24		NHRF1_HUMAN (92-255): 2.27e-21: 96.2: 22.09
+	Hs
		872669 EPHA4_HUMAN (329-626): 1.47e-105: 343: 34.54		MAGI2_HUMAN (7-240): 5.45e-10: 63.6: 12.08
+	Hs
		523212 SRC_HUMAN (4-371): 2.15e-70: 239: 15.46		SHAN2_HUMAN (66-375): 4.99e-40: 154: 19.87
+	Mm
		403435 SRC_MOUSE (4-371): 4.55e-71: 241: 15.46		SHAN3_MOUSE (68-335): 1.68e-35: 140: 17.99
+	Hs
		523133 SRC_HUMAN (4-371): 2.15e-70: 239: 15.46		SHAN3_HUMAN (72-335): 2.27e-35: 140: 18.25
+	Hs
		412342 FYN_HUMAN (4-201): 3.14e-69: 236: 22.03		SHAN3_HUMAN (72-335): 2.27e-35: 140: 18.25
+	Hs
		412287 FYN_HUMAN (4-201): 3.14e-69: 236: 22.03		MY18A_HUMAN (28-229): 1e-30: 126: 22.94
+	Hs
		338565 EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15		MAST2_HUMAN (58-393): 5.77e-38: 147: 18.48
+	Hs
		337552 ABL1_HUMAN (4-385): 1.81e-58: 214: 17.07		SHAN3_HUMAN (72-335): 2.27e-35: 140: 18.25
+	Hs
		164693 FAK1_HUMAN (344-626): 1.88e-57: 211: 39.30		MAST4_HUMAN (13-393): 3.95e-34: 136: 16.79
+	Hs
		153859 YES_HUMAN (4-203): 1.25e-68: 234: 20.80		NHRF1_HUMAN (92-255): 2.27e-21: 96.2: 22.09
+	Hs
		1070968 ERBB4_HUMAN (375-619): 7.14e-57: 210: 43.15		DLG2_HUMAN (93-381): 2.68e-21: 98.2: 14.47
+	Hs
		153911 FAK1_HUMAN (344-626): 1.88e-57: 211: 39.30		NHRF1_HUMAN (92-255): 2.27e-21: 96.2: 22.09
+	Hs
		411755 LCK_HUMAN (5-201): 3.03e-71: 240: 23.29		RHG21_HUMAN (69-190): 1.82e-10: 64.9: 24.48
+	Hs
		1070980 ERBB4_HUMAN (375-619): 7.14e-57: 210: 43.15		MAGI2_HUMAN (7-240): 5.45e-10: 63.6: 12.08
+	Mm
		1142641 ERBB4_MOUSE (375-619): 1.16e-56: 209: 43.15		MAGI2_MOUSE (21-269): 2.49e-09: 61.3: 15.81