Interactor 1: KSYK (P43405)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Gene: SYK

Interactor 2: TLR9 (Q9NR96)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23962979
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~PK_Tyr_Ser-Thr, LRR_8~SH2
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0032009 - early phagosome
GO:0032725 - positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032733 - positive regulation of interleukin-10 production
and 7 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 635
Hs

1 1032
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024