HitPredict

Interactor 1: RANG (P43487)
Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1)
Gene: RANBP1

Interactor 2: IPO4 (Q8TEX9)
Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4)
Gene: IPO4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0031267 - small GTPase binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 201 Hs			1 1081
+	Hs
		127208 RANG_HUMAN (1-201): 7.64e-63: 195: 100.00		IPO5_HUMAN (2-1081): 0: 568: 19.98
+	Hs
		127219 RBP2_HUMAN (4-164): 1.49e-44: 160: 47.83		IPO5_HUMAN (2-1081): 0: 568: 19.98
+	Hs
		312202 RANG_HUMAN (1-201): 7.64e-63: 195: 100.00		IPO7_HUMAN (1-803): 6.37e-90: 313: 12.32
+	Sc
		691631 NUP2_YEAST (3-163): 8.78e-27: 108: 22.22		IMB4_YEAST (1-1079): 2.15e-113: 380: 20.96
+	Sc
		687906 NUP2_YEAST (3-163): 8.78e-27: 108: 22.22		IMB3_YEAST (5-1079): 1.04e-109: 369: 17.81
+	Hs
		155547 RANG_HUMAN (1-201): 7.64e-63: 195: 100.00		TNPO2_HUMAN (199-1080): 9.86e-71: 256: 11.72
+	Xl
		1137361 Q6DCU3_XENLA (37-160): 2.07e-24: 100: 23.81		Q5U4V0_XENLA (194-1080): 6.93e-69: 250: 12.45
+	Hs
		796746 RANG_HUMAN (1-201): 7.64e-63: 195: 100.00		IMB1_HUMAN (332-1063): 1.95e-37: 154: 12.69
+	Hs
		483396 RGPD1_HUMAN (1-201): 7.66e-48: 169: 34.80		IMB1_HUMAN (332-1063): 1.95e-37: 154: 12.69
+	Hs
		152779 RGPD8_HUMAN (1-201): 9.54e-47: 166: 34.31		IMB1_HUMAN (332-1063): 1.95e-37: 154: 12.69
+	Hs
		834746 RBP2_HUMAN (4-164): 1.49e-44: 160: 47.83		IMB1_HUMAN (332-1063): 1.95e-37: 154: 12.69
+	Hs
		796783 RANG_HUMAN (1-201): 7.64e-63: 195: 100.00		TNPO1_HUMAN (514-1074): 1.02e-22: 107: 12.96
+	Sc
		785008 YRB1_YEAST (3-165): 2.48e-40: 137: 50.31		IMB1_YEAST (1-704): 1.63e-40: 163: 14.54
+	Hs
		1273208 RGPD5_HUMAN (1-201): 9.73e-47: 166: 34.31		TNPO1_HUMAN (514-1074): 1.02e-22: 107: 12.96
+	Hs
		1060923 RANB3_HUMAN (10-186): 4.16e-30: 117: 16.75		IMB1_HUMAN (332-1063): 1.95e-37: 154: 12.69
+	Sc
		691667 NUP2_YEAST (3-163): 8.78e-27: 108: 22.22		IMB1_YEAST (1-704): 1.63e-40: 163: 14.54
+	Hs
		834809 RBP2_HUMAN (4-164): 1.49e-44: 160: 47.83		TNPO1_HUMAN (514-1074): 1.02e-22: 107: 12.96
+	Hs
		1060962 NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02		IMB1_HUMAN (332-1063): 1.95e-37: 154: 12.69
+	Hs
		1273239 NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02		TNPO1_HUMAN (514-1074): 1.02e-22: 107: 12.96