HitPredict

Interactor 1: RANG (P43487)
Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1)
Gene: RANBP1

Interactor 2: IPO9 (Q96P70)
Importin-9 (Imp9) (Ran-binding protein 9) (RanBP9)
Gene: IPO9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031267 - small GTPase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 201 Hs			1 1041
+	Hs
		312202 RANG_HUMAN (1-201): 7.64e-63: 195: 100.00		IPO7_HUMAN (22-1040): 2.16e-162: 507: 14.21
+	Hs
		178127 RANG_HUMAN (1-201): 7.64e-63: 195: 100.00		IPO8_HUMAN (25-1039): 3.25e-157: 494: 14.66
+	Hs
		796783 RANG_HUMAN (1-201): 7.64e-63: 195: 100.00		TNPO1_HUMAN (14-878): 2.66e-148: 466: 12.42
+	Hs
		155547 RANG_HUMAN (1-201): 7.64e-63: 195: 100.00		TNPO2_HUMAN (14-878): 1.92e-140: 445: 13.05
+	Hs
		1273208 RGPD5_HUMAN (1-201): 9.73e-47: 166: 34.31		TNPO1_HUMAN (14-878): 2.66e-148: 466: 12.42
+	Hs
		834809 RBP2_HUMAN (4-164): 1.49e-44: 160: 47.83		TNPO1_HUMAN (14-878): 2.66e-148: 466: 12.42
+	Hs
		874611 NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02		XPO2_HUMAN (17-882): 4.31e-144: 457: 14.30
+	Hs
		162481 RANG_HUMAN (1-201): 7.64e-63: 195: 100.00		XPO1_HUMAN (1-923): 1.59e-108: 365: 10.42
+	Hs
		796746 RANG_HUMAN (1-201): 7.64e-63: 195: 100.00		IMB1_HUMAN (23-911): 6.16e-109: 361: 13.37
+	Hs
		152753 RGPD8_HUMAN (1-201): 9.54e-47: 166: 34.31		XPO1_HUMAN (1-923): 1.59e-108: 365: 10.42
+	Hs
		483396 RGPD1_HUMAN (1-201): 7.66e-48: 169: 34.80		IMB1_HUMAN (23-911): 6.16e-109: 361: 13.37
+	Hs
		63864 RGPD3_HUMAN (1-201): 2.17e-46: 165: 34.80		XPO1_HUMAN (1-923): 1.59e-108: 365: 10.42
+	Hs
		152779 RGPD8_HUMAN (1-201): 9.54e-47: 166: 34.31		IMB1_HUMAN (23-911): 6.16e-109: 361: 13.37
+	Hs
		162518 RBP2_HUMAN (4-164): 1.49e-44: 160: 47.83		XPO1_HUMAN (1-923): 1.59e-108: 365: 10.42
+	Hs
		834746 RBP2_HUMAN (4-164): 1.49e-44: 160: 47.83		IMB1_HUMAN (23-911): 6.16e-109: 361: 13.37
+	Sc
		691638 NUP2_YEAST (3-163): 8.78e-27: 108: 22.22		NMD5_YEAST (24-1029): 6.9e-121: 398: 14.47
+	Hs
		163286 RANB3_HUMAN (10-186): 4.16e-30: 117: 16.75		XPO1_HUMAN (1-923): 1.59e-108: 365: 10.42
+	Hs
		1060923 RANB3_HUMAN (10-186): 4.16e-30: 117: 16.75		IMB1_HUMAN (23-911): 6.16e-109: 361: 13.37
+	Hs
		163451 NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02		XPO1_HUMAN (1-923): 1.59e-108: 365: 10.42
+	Hs
		1060962 NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02		IMB1_HUMAN (23-911): 6.16e-109: 361: 13.37