HitPredict

Interactor 1: TNR4 (P43489)
Tumor necrosis factor receptor superfamily member 4 (ACT35 antigen) (OX40L receptor) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD antigen CD134)
Gene: TNFRSF4

Interactor 2: TRAF3 (Q13114)
TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3)
Gene: TRAF3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.549

Property	Details
Experiments	15941918, 9488716
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 277 Hs			1 568
+	Mm
		812913 TNR4_MOUSE (23-277): 8.81e-65: 205: 62.26		TRAF3_MOUSE (1-568): 3.65e-163: 478: 96.13
+	Hs
		591320 TNR1B_HUMAN (18-248): 6.04e-44: 156: 21.85		TRAF3_HUMAN (1-568): 1.45e-163: 479: 100.00
+	Mm
		192587 TNR11_MOUSE (6-181): 1.51e-42: 155: 27.59		TRAF3_MOUSE (1-568): 3.65e-163: 478: 96.13
+	Hs
		1024798 TNR11_HUMAN (28-181): 6.78e-37: 139: 26.40		TRAF3_HUMAN (1-568): 1.45e-163: 479: 100.00
+	Hs
		129538 TNR4_HUMAN (1-277): 7.02e-71: 221: 100.00		TRAF5_HUMAN (12-567): 9.32e-132: 397: 40.79
+	Hs
		796823 TNR4_HUMAN (1-277): 7.02e-71: 221: 100.00		TRAF2_HUMAN (11-565): 1.77e-110: 340: 30.21
+	Mm
		192584 TNR11_MOUSE (6-181): 1.51e-42: 155: 27.59		TRAF5_MOUSE (10-567): 4.83e-133: 401: 41.36
+	Mm
		761804 TNR4_MOUSE (23-277): 8.81e-65: 205: 62.26		TRAF2_MOUSE (25-565): 3.06e-110: 340: 31.16
+	Hs
		129607 TNR11_HUMAN (28-181): 6.78e-37: 139: 26.40		TRAF5_HUMAN (12-567): 9.32e-132: 397: 40.79
+	Hs
		591317 TNR1B_HUMAN (18-248): 6.04e-44: 156: 21.85		TRAF2_HUMAN (11-565): 1.77e-110: 340: 30.21
+	Mm
		192583 TNR11_MOUSE (6-181): 1.51e-42: 155: 27.59		TRAF2_MOUSE (25-565): 3.06e-110: 340: 31.16
+	Hs
		796824 TNR4_HUMAN (1-277): 7.02e-71: 221: 100.00		TRAF1_HUMAN (151-563): 2.25e-80: 260: 32.63
+	Hs
		1021008 TNR11_HUMAN (28-181): 6.78e-37: 139: 26.40		TRAF2_HUMAN (11-565): 1.77e-110: 340: 30.21
+	Hs
		796826 TNR4_HUMAN (1-277): 7.02e-71: 221: 100.00		TRAF4_HUMAN (37-562): 2.06e-77: 254: 23.15
+	Mm
		761775 TNR4_MOUSE (23-277): 8.81e-65: 205: 62.26		TRAF1_MOUSE (151-563): 6.69e-79: 256: 33.25
+	Mm
		192585 TNR11_MOUSE (6-181): 1.51e-42: 155: 27.59		TRAF6_MOUSE (20-562): 1.2e-84: 275: 20.48
+	Hs
		591438 TNR1B_HUMAN (18-248): 6.04e-44: 156: 21.85		TRAF6_HUMAN (22-562): 7.2e-84: 272: 21.28
+	Hs
		591319 TNR1B_HUMAN (18-248): 6.04e-44: 156: 21.85		TRAF1_HUMAN (151-563): 2.25e-80: 260: 32.63
+	Hs
		1023848 TNR11_HUMAN (28-181): 6.78e-37: 139: 26.40		TRAF1_HUMAN (151-563): 2.25e-80: 260: 32.63
+	Hs
		301610 TNR1B_HUMAN (18-248): 6.04e-44: 156: 21.85		TRI37_HUMAN (39-322): 1.6e-14: 78.9: 12.98