Interactor 1: NAMPT (P43490)
Nicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (EC 2.4.2.12) (Pre-B-cell colony-enhancing factor 1) (Pre-B cell-enhancing factor) (Visfatin)
Gene: NAMPT

Interactor 2: NAMPT (P43490)
Nicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (EC 2.4.2.12) (Pre-B-cell colony-enhancing factor 1) (Pre-B cell-enhancing factor) (Visfatin)
Gene: NAMPT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.820

The method score is based on:

Property Details
Experiments 16783377, 19666527
Identification Methods x-ray crystallography, molecular sieving, light scattering
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains NAMPT_N~NAPRTase, NAPRTase~NAPRTase
Common GO terms GO:0005125 - cytokine activity
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0007267 - cell-cell signaling
GO:0008284 - positive regulation of cell population proliferation
and 9 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 491
Hs

1 491
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024