Interactor 1: CASP1 (P43527)
Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]
Gene: CASP1

Interactor 2: CASPC (Q920D5)
Caspase-12 (CASP-12) (EC 3.4.22.-)
Gene: Casp12

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 18332441
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CARD~CARD, Peptidase_C14~Peptidase_C14
Common GO terms GO:0004175 - endopeptidase activity
GO:0004197 - cysteine-type endopeptidase activity
GO:0005737 - cytoplasm
GO:0009410 - response to xenobiotic stimulus
GO:0016540 - protein autoprocessing
and 6 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 402
Rn

1 420
+ Hs
+ Rn
+ Mm
+ Mm
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+ Mm
+ Hs
+ Hs
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+ Hs
+ Hs
+ Hs
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+ Hs

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Last updated: 15 Jul 2024