Interactor 1: THI5 (P43534)
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI5 (HMP-P synthase) (Hydroxymethylpyrimidine phosphate synthase) (EC 2.-.-.-) (Thiamine biosynthesis protein 5) (Thiamine pyrimidine synthase)
Gene: THI5

Interactor 2: THI5 (P43534)
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI5 (HMP-P synthase) (Hydroxymethylpyrimidine phosphate synthase) (EC 2.-.-.-) (Thiamine biosynthesis protein 5) (Thiamine pyrimidine synthase)
Gene: THI5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 23048037
Identification Methods x-ray crystallography
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains NMT1~NMT1
Common GO terms GO:0005506 - iron ion binding
GO:0009228 - thiamine biosynthetic process
GO:0009229 - thiamine diphosphate biosynthetic process
GO:0106344 - 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 340
Sc

1 340
+ Ca

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Last updated: 15 Jul 2024