HitPredict

Interactor 1: SNZ3 (P43545)
Probable pyridoxal 5'-phosphate synthase subunit SNZ3 (PLP synthase subunit SNZ3) (EC 4.3.3.6) (PDX1 homolog 3) (Pdx1.3)
Gene: SNZ3

Interactor 2: SNO1 (Q03144)
Pyridoxal 5'-phosphate synthase subunit SNO1 (EC 4.3.3.6) (PDX2 homolog 1) (Pdx2.1) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2)
Gene: SNO1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.850

Property	Details
Experiments	11283351, 10655498, 10688190
Identification Methods	two hybrid pooling approach, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	SNO~SOR_SNZ
Common GO terms	GO:0008615 - pyridoxine biosynthetic process GO:0036381 - pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity GO:0042823 - pyridoxal phosphate biosynthetic process
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 298 Sc			1 224
+	Sc
		865170 SNZ2_YEAST (1-298): 5.18e-175: 487: 99.66		SNO1_YEAST (1-224): 1.29e-124: 353: 100.00
+	Sc
		975162 SNZ1_YEAST (3-298): 8.55e-162: 453: 80.74		SNO1_YEAST (1-224): 1.29e-124: 353: 100.00
+	Sc
		796972 SNZ3_YEAST (1-298): 5.47e-175: 487: 100.00		SNO3_YEAST (15-222): 2.75e-102: 297: 67.14
+	Sc
		796973 SNZ2_YEAST (1-298): 5.18e-175: 487: 99.66		SNO3_YEAST (15-222): 2.75e-102: 297: 67.14
+	Sc
		796978 SNZ3_YEAST (1-298): 5.47e-175: 487: 100.00		SNO2_YEAST (15-222): 5.49e-102: 296: 66.67
+	Sc
		865166 SNZ2_YEAST (1-298): 5.18e-175: 487: 99.66		SNO2_YEAST (15-222): 5.49e-102: 296: 66.67
+	Sc
		796976 SNZ1_YEAST (3-298): 8.55e-162: 453: 80.74		SNO3_YEAST (15-222): 2.75e-102: 297: 67.14
+	Sc
		865168 SNZ1_YEAST (3-298): 8.55e-162: 453: 80.74		SNO2_YEAST (15-222): 5.49e-102: 296: 66.67
+	At
		1226677 PDX13_ARATH (2-281): 6.44e-166: 464: 65.36		PDX2_ARATH (15-219): 2.01e-80: 242: 34.96
+	At
		285347 PDX11_ARATH (2-291): 1.89e-161: 453: 62.76		PDX2_ARATH (15-219): 2.01e-80: 242: 34.96
+	Sp
		144183 PDX1_SCHPO (5-298): 7.3e-157: 441: 65.99		YFM8_SCHPO (3-222): 6.36e-80: 240: 37.72
+	Pf
		86932 PDX1_PLAF7 (6-276): 9.5e-149: 420: 59.41		PDX2_PLAF7 (15-221): 4.41e-75: 227: 35.62
+	Bs
		741664 PDXS_BACSU (5-298): 8.96e-150: 423: 58.50		PDXT_BACSU (13-219): 6.72e-72: 218: 36.72
+	Ph
		223429 PDXS_PYRHO (5-297): 6.79e-142: 404: 50.00		PDXT_PYRHO (16-222): 1.2e-76: 231: 40.67