HitPredict

Interactor 1: RGD2 (P43556)
Rho-GTPase-activating protein RGD2
Gene: RGD2

Interactor 2: RHO5 (P53879)
GTP-binding protein RHO5
Gene: RHO5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	11591390
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 714 Sc			1 331
+	Sc
		580323 RGD2_YEAST (1-714): 0: 833: 100.00		CDC42_YEAST (1-229): 9.1e-97: 286: 42.80
+	Hs
		901050 PACN2_HUMAN (5-403): 6.44e-97: 309: 15.11		RHOA_HUMAN (5-229): 1.44e-77: 237: 40.89
+	Hs
		925732 PACN2_HUMAN (5-403): 6.44e-97: 309: 15.11		RAC1_HUMAN (1-230): 8.61e-76: 232: 43.91
+	Hs
		892680 PACN2_HUMAN (5-403): 6.44e-97: 309: 15.11		RAC3_HUMAN (1-218): 5.72e-73: 225: 44.95
+	Hs
		951457 PACN2_HUMAN (5-403): 6.44e-97: 309: 15.11		RHOG_HUMAN (1-229): 1.07e-72: 225: 41.92
+	Hs
		894589 PACN2_HUMAN (5-403): 6.44e-97: 309: 15.11		CDC42_HUMAN (1-229): 1.18e-70: 219: 44.11
+	Hs
		901035 PACN3_HUMAN (4-403): 9.15e-87: 281: 14.29		RHOA_HUMAN (5-229): 1.44e-77: 237: 40.89
+	Hs
		925717 PACN3_HUMAN (4-403): 9.15e-87: 281: 14.29		RAC1_HUMAN (1-230): 8.61e-76: 232: 43.91
+	Hs
		892672 PACN3_HUMAN (4-403): 9.15e-87: 281: 14.29		RAC3_HUMAN (1-218): 5.72e-73: 225: 44.95
+	Hs
		894574 PACN3_HUMAN (4-403): 9.15e-87: 281: 14.29		CDC42_HUMAN (1-229): 1.18e-70: 219: 44.11
+	Hs
		564738 PACN2_HUMAN (5-403): 6.44e-97: 309: 15.11		RHOQ_HUMAN (4-222): 7.24e-56: 182: 42.92
+	Hs
		564730 PACN3_HUMAN (4-403): 9.15e-87: 281: 14.29		RHOQ_HUMAN (4-222): 7.24e-56: 182: 42.92
+	Hs
		925540 FNBP1_HUMAN (9-288): 8.43e-57: 205: 13.29		RAC1_HUMAN (1-230): 8.61e-76: 232: 43.91
+	Hs
		894037 CIP4_HUMAN (9-390): 1.31e-59: 213: 14.76		CDC42_HUMAN (1-229): 1.18e-70: 219: 44.11
+	Hs
		892549 FNBP1_HUMAN (9-288): 8.43e-57: 205: 13.29		RAC3_HUMAN (1-218): 5.72e-73: 225: 44.95
+	Hs
		951252 FNBP1_HUMAN (9-288): 8.43e-57: 205: 13.29		RHOG_HUMAN (1-229): 1.07e-72: 225: 41.92
+	Hs
		894338 FNBP1_HUMAN (9-288): 8.43e-57: 205: 13.29		CDC42_HUMAN (1-229): 1.18e-70: 219: 44.11
+	Hs
		892416 FBP1L_HUMAN (9-226): 1.55e-51: 190: 14.80		RAC3_HUMAN (1-218): 5.72e-73: 225: 44.95
+	Hs
		564542 CIP4_HUMAN (9-390): 1.31e-59: 213: 14.76		RHOQ_HUMAN (4-222): 7.24e-56: 182: 42.92
+	Hs
		564653 FNBP1_HUMAN (9-288): 8.43e-57: 205: 13.29		RHOQ_HUMAN (4-222): 7.24e-56: 182: 42.92