Interactor 1: OTU1 (P43558)
Ubiquitin thioesterase OTU1 (EC 3.4.19.12) (OTU domain-containing protein 1)
Gene: OTU1
Interactor 2: HRD1 (Q08109)
ERAD-associated E3 ubiquitin-protein ligase HRD1 (EC 2.3.2.27) (HMG-CoA reductase degradation protein 1) (RING-type E3 ubiquitin transferase HRD1)
Gene: HRD1
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.53 | 0.60 | 0.569 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25215493 |
| Identification Methods | enzymatic study, deubiquitinase assay |
| Interaction Type | direct interaction, deubiquitination reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0030968 - endoplasmic reticulum unfolded protein response GO:0036503 - ERAD pathway GO:0046872 - metal ion binding |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
