Interactor 1: RPN11 (P43588)
Ubiquitin carboxyl-terminal hydrolase RPN11 (EC 3.4.19.12) (26S proteasome regulatory subunit RPN11) (Protein MPR1)
Gene: RPN11

Interactor 2: UBP6 (P43593)
Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.4.19.12) (Deubiquitinating enzyme 6) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6)
Gene: UBP6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.765

The method score is based on:

Property Details
Experiments 11805826, 16284124, 16338358, 22215586, 24038880, 26450923, 26601941, 12408819, 26182356, 19153599, 37968396, 34161281, 27405762, 31601863, 21321079, 21627799, 21878652, 22237024, 23770819, 14581483 and 2 others

more...

Identification Methods tandem affinity purification, affinity chromatography technology, biochemical, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000502 - proteasome complex
GO:0004843 - cysteine-type deubiquitinase activity
GO:0016579 - protein deubiquitination
GO:0070628 - proteasome binding
Homologous interactions 14

Homologous interactions

Color coding for hit scores

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Sc

1 499
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Last updated: 15 Jul 2024