HitPredict

Interactor 1: RPN11 (P43588)
Ubiquitin carboxyl-terminal hydrolase RPN11 (EC 3.4.19.12) (26S proteasome regulatory subunit RPN11) (Protein MPR1)
Gene: RPN11

Interactor 2: YE11B (Q03612)
Transposon Ty1-ER1 Gag-Pol polyprotein (Gag-Pol-p199) (TY1A-TY1B) (Transposon Ty1 TYA-TYB polyprotein) (p190) [Cleaved into: Capsid protein (CA) (Gag-p45) (p54); Ty1 protease (PR) (EC 3.4.23.-) (Pol-p20) (p23); Integrase (IN) (Pol-p71) (p84) (p90); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (Pol-p63) (p60)]
Gene: TY1B-ER1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20170199
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 306 Sc			1 1755
+	Sc
		797645 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YO11B_YEAST (1-1755): 0: 2879: 99.72
+	Sc
		472544 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YD14B_YEAST (1-1755): 0: 2852: 98.52
+	Sc
		797454 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YJ12B_YEAST (1-1755): 0: 2838: 97.78
+	Sc
		797579 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YM14B_YEAST (1-1755): 0: 2836: 97.89
+	Sc
		797631 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YG11B_YEAST (1-1755): 0: 2835: 97.61
+	Sc
		797647 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YG13B_YEAST (1-1755): 0: 2783: 96.13
+	Sc
		797558 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YE12B_YEAST (1-1755): 0: 2781: 96.47
+	Sc
		797625 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YL11B_YEAST (1-1755): 0: 2779: 96.52
+	Sc
		797636 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YB12B_YEAST (1-1755): 0: 2762: 95.44
+	Sc
		797627 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YN11B_YEAST (1-1755): 0: 2759: 92.93
+	Sc
		797573 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YM13B_YEAST (1-1755): 0: 2731: 91.40
+	Sc
		797662 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YB11B_YEAST (1-1755): 0: 2726: 91.34
+	Sc
		797624 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YG11A_YEAST (1-435): 0: 791: 98.62
+	Sc
		482571 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YA11A_YEAST (1-438): 0: 789: 98.17
+	Sc
		482627 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YE11A_YEAST (1-435): 0: 767: 100.00
+	Sc
		251219 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YD13A_YEAST (1-435): 0: 765: 99.77
+	Sc
		482636 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YL13A_YEAST (1-435): 0: 765: 99.77
+	Sc
		472597 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YL14A_YEAST (1-435): 0: 763: 99.54
+	Sc
		797661 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YG12A_YEAST (1-435): 0: 761: 98.62
+	Sc
		797563 RPN11_YEAST (1-306): 4.59e-91: 274: 100.00		YD11A_YEAST (1-435): 0: 755: 97.93