HitPredict

Interactor 1: RPN11 (P43588)
Ubiquitin carboxyl-terminal hydrolase RPN11 (EC 3.4.19.12) (26S proteasome regulatory subunit RPN11) (Protein MPR1)
Gene: RPN11

Interactor 2: RPN6 (Q12377)
26S proteasome regulatory subunit RPN6 (Proteasome non-ATPase subunit 4)
Gene: RPN6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.990

The method score is based on:

Property Details
Experiments 11805826, 16284124, 16338358, 22215586, 26744777, 16429126, 26182356, 28106073, 26929360, 18314965, 34161281, 27405762, 31601863, 15917626, 21321079, 21627799, 21658604, 22237024, 23770819, 22927375 and 8 others

more...
Identification Methods tandem affinity purification, affinity chromatography technology, biochemical, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~PCI
Common GO terms GO:0000502 - proteasome complex
GO:0008541 - proteasome regulatory particle, lid subcomplex
GO:0034515 - proteasome storage granule
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043248 - proteasome assembly
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 306
Sc

1 434
+ Dm
+ Hs
+ Sp
+ Dm
+ Hs
+ Dm
+ Mm
+ Hs
+ At
+ At
+ Ce
+ Mm
+ At
+ At
+ Mm
+ Hs
+ Hs
+ Mm
+ Ce
+ Dm

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Last updated: 15 Jul 2024