HitPredict

Interactor 1: UBP6 (P43593)
Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.4.19.12) (Deubiquitinating enzyme 6) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6)
Gene: UBP6

Interactor 2: PRS10 (P53549)
26S proteasome subunit RPT4 (26S protease subunit SUG2) (Proteasomal cap subunit)
Gene: RPT4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.896

Property	Details
Experiments	11805826, 16554755, 16429126, 37968396
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Prot_ATP_ID_OB~UCH
Common GO terms	GO:0000502 - proteasome complex
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 499 Sc			1 437
+	Hs
		870729 UBP14_HUMAN (5-499): 1.27e-103: 320: 29.12		PRS8_HUMAN (43-437): 1.18e-135: 397: 41.29
+	Sp
		251479 UBP6_SCHPO (5-499): 1.89e-113: 345: 37.02		PRS10_SCHPO (52-437): 2.31e-121: 360: 74.61
+	Hs
		870733 UBP14_HUMAN (5-499): 1.27e-103: 320: 29.12		PRS10_HUMAN (51-437): 1.51e-129: 381: 67.70
+	Hs
		870728 UBP14_HUMAN (5-499): 1.27e-103: 320: 29.12		PRS4_HUMAN (27-428): 6.56e-126: 373: 38.24
+	Sc
		797710 UBP6_YEAST (1-495): 9.09e-119: 359: 100.00		PRS8_YEAST (73-437): 2.68e-99: 304: 44.89
+	Hs
		907177 UBP36_HUMAN (3-496): 3.71e-76: 261: 14.46		PRS8_HUMAN (43-437): 1.18e-135: 397: 41.29
+	Sc
		703921 UBP6_YEAST (1-495): 9.09e-119: 359: 100.00		PRS7_YEAST (116-436): 9.22e-93: 289: 46.89
+	Hs
		870712 UBP14_HUMAN (5-499): 1.27e-103: 320: 29.12		TERA_HUMAN (23-433): 3.62e-79: 262: 26.83
+	Hs
		874936 UBP10_HUMAN (2-499): 2.81e-76: 257: 14.18		TERA_HUMAN (23-433): 3.62e-79: 262: 26.83
+	Hs
		849967 UBP11_HUMAN (325-499): 1.73e-30: 127: 18.64		TERA_HUMAN (23-433): 3.62e-79: 262: 26.83
+	Hs
		875191 UBP7_HUMAN (100-347): 5.03e-30: 126: 21.26		TERA_HUMAN (23-433): 3.62e-79: 262: 26.83
+	Hs
		798619 UBP14_HUMAN (5-499): 1.27e-103: 320: 29.12		PRS6B_HUMAN (1-123): 4.23e-09: 60.2: 8.03
+	Dm
		186175 X2JLM6_DROME (65-496): 7.48e-76: 250: 15.51		PRS8_DROME (1-147): 2.61e-09: 60.9: 9.32
+	Hs
		798616 UBP11_HUMAN (325-499): 1.73e-30: 127: 18.64		PRS6B_HUMAN (1-123): 4.23e-09: 60.2: 8.03