HitPredict

Interactor 1: KI2L3 (P43628)
Killer cell immunoglobulin-like receptor 2DL3 (CD158 antigen-like family member B2) (KIR-023GB) (Killer inhibitory receptor cl 2-3) (NKAT2a) (NKAT2b) (Natural killer-associated transcript 2) (NKAT-2) (p58 natural killer cell receptor clone CL-6) (p58 NK receptor CL-6) (p58.2 MHC class-I-specific NK receptor) (CD antigen CD158b2)
Gene: KIR2DL3

Interactor 2: PTN11 (Q06124)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)
Gene: PTPN11

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.50	0.442

Property	Details
Experiments	8648092
Identification Methods	pull down, surface plasmon resonance
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 341 Hs			1 593
+	Hs
		798139 KI2L1_HUMAN (1-340): 1.84e-126: 368: 90.59		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Hs
		986023 KI2L4_HUMAN (1-341): 1.02e-122: 359: 63.05		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Hs
		665820 KI2L3_HUMAN (1-341): 4.64e-132: 381: 100.00		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Hs
		665819 KI2L1_HUMAN (1-340): 1.84e-126: 368: 90.59		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Mm
		719307 LRB4A_MOUSE (1-336): 7.44e-72: 228: 27.43		PTN11_MOUSE (1-593): 0: 580: 99.49
+	Hs
		798232 KI3L1_HUMAN (1-251): 2.24e-63: 209: 38.19		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Hs
		252776 LIRB3_HUMAN (1-296): 1.22e-68: 227: 27.67		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Mm
		665991 LRB4A_MOUSE (1-336): 7.44e-72: 228: 27.43		PTN6_MOUSE (6-583): 0: 530: 55.94
+	Hs
		616953 KI2L1_HUMAN (1-340): 1.84e-126: 368: 90.59		PTPRD_HUMAN (39-522): 2.1e-115: 379: 26.76
+	Hs
		665821 KI3L1_HUMAN (1-251): 2.24e-63: 209: 38.19		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Hs
		685206 FCG2B_HUMAN (8-317): 8.68e-43: 151: 16.15		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Hs
		986005 FCGRB_HUMAN (5-274): 3.22e-42: 149: 19.57		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Hs
		985972 LAIR1_HUMAN (1-144): 6.7e-38: 138: 25.83		PTN11_HUMAN (1-593): 0: 581: 100.00
+	Mm
		719316 Q8K4V6_MOUSE (21-258): 1.02e-34: 136: 26.34		PTN11_MOUSE (1-593): 0: 580: 99.49
+	Mm
		719293 LIRB3_MOUSE (21-258): 1.97e-33: 132: 25.93		PTN11_MOUSE (1-593): 0: 580: 99.49
+	Hs
		665916 LIRB2_HUMAN (17-341): 1.02e-45: 165: 30.56		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Hs
		665804 FCG2B_HUMAN (8-317): 8.68e-43: 151: 16.15		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Hs
		665902 LAIR1_HUMAN (1-144): 6.7e-38: 138: 25.83		PTN6_HUMAN (6-593): 0: 531: 55.27
+	Mm
		665982 LIRB3_MOUSE (21-258): 1.97e-33: 132: 25.93		PTN6_MOUSE (6-583): 0: 530: 55.94
+	Hs
		616999 LIRB4_HUMAN (17-337): 4.91e-30: 120: 24.22		PTPRD_HUMAN (39-522): 2.1e-115: 379: 26.76