HitPredict

Interactor 1: KI3L1 (P43629)
Killer cell immunoglobulin-like receptor 3DL1 (CD158 antigen-like family member E) (HLA-BW4-specific inhibitory NK cell receptor) (Natural killer-associated transcript 3) (NKAT-3) (p70 natural killer cell receptor clones CL-2/CL-11) (p70 NK receptor CL-2/CL-11) (CD antigen CD158e)
Gene: KIR3DL1

Interactor 2: B2MG (P61769)
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
Gene: B2M

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27649529
Identification Methods	surface plasmon resonance
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1-set~ig
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 119
+	Hs
		673944 KI3L1_HUMAN (1-444): 1.25e-115: 347: 100.00		HLAF_HUMAN (2-116): 3.24e-45: 151: 25.00
+	Hs
		354352 KI3L1_HUMAN (1-444): 1.25e-115: 347: 100.00		HLAB_HUMAN (2-117): 7.05e-44: 148: 19.66
+	Hs
		382341 KI3L2_HUMAN (1-444): 2.77e-112: 339: 85.59		HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41
+	Hs
		570311 KI3L1_HUMAN (1-444): 1.25e-115: 347: 100.00		HLAG_HUMAN (2-116): 6.98e-44: 147: 22.41
+	Hs
		798244 KI3L2_HUMAN (1-444): 2.77e-112: 339: 85.59		Q5S3G3_HUMAN (2-116): 3.35e-46: 154: 22.41
+	Hs
		673945 KI3L2_HUMAN (1-444): 2.77e-112: 339: 85.59		HLAF_HUMAN (2-116): 3.24e-45: 151: 25.00
+	Hs
		354353 KI3L2_HUMAN (1-444): 2.77e-112: 339: 85.59		HLAB_HUMAN (2-117): 7.05e-44: 148: 19.66
+	Hs
		47499 A0A8I5QEB2_HUMAN (1-427): 3.73e-100: 306: 72.83		HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41
+	Hs
		488296 KI3L3_HUMAN (1-427): 2.29e-100: 307: 73.30		HLAC_HUMAN (2-117): 4.98e-46: 153: 19.66
+	Hs
		47500 A0A8I5QEB2_HUMAN (1-427): 3.73e-100: 306: 72.83		HLAC_HUMAN (2-117): 4.98e-46: 153: 19.66
+	Hs
		47498 A0A8I5QEB2_HUMAN (1-427): 3.73e-100: 306: 72.83		HLAB_HUMAN (2-117): 7.05e-44: 148: 19.66
+	Hs
		382420 KI3S1_HUMAN (1-369): 9.59e-97: 297: 95.66		HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41
+	Hs
		1060406 KI3S1_HUMAN (1-369): 9.59e-97: 297: 95.66		Q95J06_HUMAN (2-117): 5.6e-46: 153: 22.22
+	Hs
		488221 KI3S1_HUMAN (1-369): 9.59e-97: 297: 95.66		HLAC_HUMAN (2-117): 4.98e-46: 153: 19.66
+	Hs
		1060402 KI3S1_HUMAN (1-369): 9.59e-97: 297: 95.66		Q546I9_HUMAN (2-117): 2.02e-45: 152: 21.37
+	Hs
		673954 KI3S1_HUMAN (1-369): 9.59e-97: 297: 95.66		HLAF_HUMAN (2-116): 3.24e-45: 151: 25.00
+	Hs
		1060403 KI3S1_HUMAN (1-369): 9.59e-97: 297: 95.66		Q5SUL5_HUMAN (2-116): 2.45e-44: 149: 22.41
+	Hs
		354449 KI3S1_HUMAN (1-369): 9.59e-97: 297: 95.66		HLAB_HUMAN (2-117): 7.05e-44: 148: 19.66
+	Hs
		901870 KI3S1_HUMAN (1-369): 9.59e-97: 297: 95.66		B2MG_HUMAN (1-119): 1.69e-42: 137: 100.00
+	Hs
		382306 FGFR2_HUMAN (2-391): 9.5e-60: 210: 13.89		HLAA_HUMAN (2-116): 6.86e-47: 155: 22.41